听力与言语-语言病理学

行为科学

医学伦理学

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  • Psychological stress, cytokine production, and severity of upper respiratory illness.

    abstract:OBJECTIVE:The purpose of this study is to assess the role of psychological stress in the expression of illness among infected subjects and to test the plausibility of local proinflammatory cytokine production as a pathway linking stress to illness. METHODS:After completing a measure of psychological stress, 55 subject...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199903000-00009

    authors: Cohen S,Doyle WJ,Skoner DP

    更新日期:1999-03-01 00:00:00

  • Anxiety but not depression is associated with elevated blood pressure in a community group of French elderly.

    abstract:OBJECTIVE:This study examined whether anxiety and depression were independently associated with elevated blood pressure in elderly persons. METHOD:The study group consisted of 1389 subjects aged 59 to 71 years recruited from the electoral rolls of the city of Nantes (France). Subjects completed the Center for Epidemio...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199901000-00013

    authors: Paterniti S,Alpérovitch A,Ducimetière P,Dealberto MJ,Lépine JP,Bisserbe JC

    更新日期:1999-01-01 00:00:00

  • Stressful events, pessimism, natural killer cell cytotoxicity, and cytotoxic/suppressor T cells in HIV+ black women at risk for cervical cancer.

    abstract:OBJECTIVE:This study examines whether stressful negative life events and pessimism were associated with lower natural killer cell cytotoxicity (NKCC) and T cytotoxic/suppressor cell (CD8+CD3+) percentage in black women co-infected with human immunodeficiency virus Type 1 (HIV-1) and human papillomavirus (HPV), a viral ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199811000-00009

    authors: Byrnes DM,Antoni MH,Goodkin K,Efantis-Potter J,Asthana D,Simon T,Munajj J,Ironson G,Fletcher MA

    更新日期:1998-11-01 00:00:00

  • Are hostility and anxiety associated with carotid atherosclerosis in healthy postmenopausal women?

    abstract:OBJECTIVE:In this article, we evaluated the prospective association between measures of trait anger, hostility, and anxiety and indices of carotid atherosclerosis in 200 healthy middle-aged postmenopausal women. METHODS:Starting in 1983, 541 premenopausal women were evaluated for their levels of standard cardiovascula...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199809000-00021

    authors: Matthews KA,Owens JF,Kuller LH,Sutton-Tyrrell K,Jansen-McWilliams L

    更新日期:1998-09-01 00:00:00

  • Diagnostic groups and depressed mood as predictors of 22-month mortality in medical inpatients.

    abstract:OBJECTIVE:While depression has been found to predict mortality in acute myocardial infarction, results from many other groups of medical patients are inconclusive. It is, therefore, unclear whether depression also predicts mortality in the typical mixed patient populations treated on medical hospital wards and whether ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199809000-00011

    authors: Herrmann C,Brand-Driehorst S,Kaminsky B,Leibing E,Staats H,Rüger U

    更新日期:1998-09-01 00:00:00

  • Hypothalamic-pituitary-adrenocortical responses to psychological stress and caffeine in men at high and low risk for hypertension.

    abstract:OBJECTIVE:This study examined pituitary-adrenocortical responses to dietary doses of caffeine (3.3 mg/kg, equivalent to 2 to 3 cups of coffee), alone and combined with behavioral stress, in men at high risk versus low risk for hypertension. A randomized, double-blind, caffeine-placebo crossover design was used. METHOD...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199807000-00021

    authors: al'Absi M,Lovallo WR,McKey B,Sung BH,Whitsett TL,Wilson MF

    更新日期:1998-07-01 00:00:00

  • Estranged bodies, simulated harmony, and misplaced cultures: neurasthenia in contemporary Chinese society.

    abstract:OBJECTIVE:To study the sociocultural transformation of neurasthenia (shenjing shuairuo, SJSR), as both disease and illness, in Chinese society. METHOD:This is based on a critical review of evidence drawn from the psychiatric and anthropological literature, and the use of a single case study. RESULTS:SJSR remains a ub...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199807000-00010

    authors: Lee S

    更新日期:1998-07-01 00:00:00

  • Caffeine raises blood pressure at work.

    abstract:OBJECTIVE:The study investigated the effects of moderate doses of caffeine on ambulatory blood pressure and heart rate during workday activities. METHODS:Healthy, nonsmoking, habitual coffee drinkers (N = 21) received daily doses of 100 mg and 500 mg of caffeine on 2 days in a crossover design. Treatment order was ran...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199805000-00019

    authors: Lane JD,Phillips-Bute BG,Pieper CF

    更新日期:1998-05-01 00:00:00

  • Psychosocial work characteristics and social support as predictors of SF-36 health functioning: the Whitehall II study.

    abstract:OBJECTIVE:To assess whether work characteristics and social support are predictors of physical, psychological, and social functioning. METHOD:Work characteristics (Karasek and Siegrist models) and social support at baseline were used to predict health functioning measured by the SF-36 General Health Survey 5 years lat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199805000-00004

    authors: Stansfeld SA,Bosma H,Hemingway H,Marmot MG

    更新日期:1998-05-01 00:00:00

  • Elevated levels of psychophysiological arousal and cortisol in patients with somatization syndrome.

    abstract:OBJECTIVE:This study investigates psychological and psychobiological processes in patients with somatization syndrome. METHOD:We compared physiological measures (heart rate, finger pulse volume, electrodermal activity, electromyography), cortisol levels, and subjective well-being during rest and during a mental stress...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199803000-00016

    authors: Rief W,Shaw R,Fichter MM

    更新日期:1998-03-01 00:00:00

  • Hypocapnia associated with cardiac stress scintigraphy in chest pain patients with panic disorder.

    abstract:OBJECTIVE:Patients with recurrent chest pain but no evidence of coronary artery disease often meet diagnostic criteria for panic disorder (PD). However, it can be argued that the phenomenological diagnosis of PD may not be valid in these normal coronary chest pain (NCCP) patients. The purpose of this study is to additi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199801000-00013

    authors: Maddock RJ,Carter CS,Tavano-Hall L,Amsterdam EA

    更新日期:1998-01-01 00:00:00

  • The relationship between hostility and beta-adrenergic receptor physiology in health young males.

    abstract:OBJECTIVE:We examined the relationship between hostility and mononuclear leukocyte (MNL) beta-adrenergic receptor function in a sample of young healthy males. METHOD:Thirty subjects were selected for having scored above 20 (N = 11) and below 14 (N = 19) on the Cook-Medley Hostility (Ho) scale. MNL beta-adrenergic rece...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199709000-00004

    authors: Suarez EC,Shiller AD,Kuhn CM,Schanberg S,Williams RB Jr,Zimmermann EA

    更新日期:1997-09-01 00:00:00

  • Inhibition of subjective and physiological sexual arousal in women by clonidine.

    abstract:OBJECTIVE:The present investigation was designed to provide the first empirical examination of the effects of clonidine, a selective alpha 2-adrenergic agonist, on sexual arousal in women with and without prior sympathetic nervous system [SNS] stimulation by exercise. The purpose was to help elucidate the influence of ...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199707000-00010

    authors: Meston CM,Gorzalka BB,Wright JM

    更新日期:1997-07-01 00:00:00

  • Smoking status and nicotine administration differentially modify hemodynamic stress reactivity in men and women.

    abstract:OBJECTIVES:To investigate the impact of cigarette smoking and oral contraceptive (OC) use on hemodynamic stress responses of women. Also, to examine gender differences in stress reactivity as a function of smoking status and acute nicotine administration. METHODS:Thirty men and 46 women, differing in smoking status an...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199705000-00012

    authors: Girdler SS,Jamner LD,Jarvik M,Soles JR,Shapiro D

    更新日期:1997-05-01 00:00:00

  • Perceptions of parental caring predict health status in midlife: a 35-year follow-up of the Harvard Mastery of Stress Study.

    abstract:OBJECTIVE:This study examined how the perception of parental caring, obtained from undergraduates, relates to subsequent health over the ensuing 35 years. METHODS:In the early 1950s, initial ratings of parental caring were obtained from a sample of healthy, Harvard undergraduate men who participated in the Harvard Mas...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199703000-00005

    authors: Russek LG,Schwartz GE

    更新日期:1997-03-01 00:00:00

  • Transgenic and null mutant animals for psychosomatic research.

    abstract:OBJECTIVE:Progress in the use of genetically altered animals for psychosomatic research is reviewed. METHOD:Analysis of the strengths and weaknesses of these models, particularly from a developmental and behavioral prospective is used to assess the validity of these models. RESULTS:Genetically altered animals can be ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199611000-00010

    authors: Crnic LS

    更新日期:1996-11-01 00:00:00

  • Insulin and glucose: relationships with hassles, anger, and hostility in nondiabetic older adults.

    abstract::Relationships of psychosocial factors (anger, hostility, hassles, and caregiving) with fasting insulin and glucose levels were examined. Samples included two groups of nondiabetic adults (mean age = 69.4 years): spouse caregivers (CG) of individuals with diagnoses of Alzheimer's disease (AD) (N = 78) and spouses of no...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199609000-00011

    authors: Vitaliano PP,Scanlan JM,Krenz C,Fujimoto W

    更新日期:1996-09-01 00:00:00

  • Is anxiety early after myocardial infarction associated with subsequent ischemic and arrhythmic events?

    abstract:OBJECTIVE:Acute myocardial infarction is often accompanied by anxiety, but the effect of this emotion on recovery is unclear. The purpose of this study was to determine the association between patient anxiety early after acute myocardial infarction and the incidence of subsequent in-hospital complications. METHODS:We ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00006842-199609000-00001

    authors: Moser DK,Dracup K

    更新日期:1996-09-01 00:00:00

  • Psychological stress as a determinant of protein levels and salivary-induced aggregation of Streptococcus gordonii in human whole saliva.

    abstract::Several pathologies of the oral cavity have been associated with stress, so we investigated salivary-induced aggregation during psychological stress. In addition, salivary total protein, alpha-amylase, and secretory immunoglobulin A (s-IgA) were assessed. In this longitudinal study, 28 dental students provided unstimu...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199607000-00010

    authors: Bosch JA,Brand HS,Ligtenberg TJ,Bermond B,Hoogstraten J,Nieuw Amerongen AV

    更新日期:1996-07-01 00:00:00

  • The influence of stress intrusion on immunodepression in generalized anxiety disorder patients and controls.

    abstract::Previous work from our group has examined the relationship between stress and immunodepression in medical students taking National Boards, Part I, and has described a relationship between stress intrusion scores (SIS) and immunodepression. We have also shown that a high proportion of individuals with generalized anxie...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199603000-00007

    authors: La Via MF,Munno I,Lydiard RB,Workman EW,Hubbard JR,Michel Y,Paulling E

    更新日期:1996-03-01 00:00:00

  • Relationship of optimism, knowledge, attitudes, and beliefs to use of HIV antibody testing by at-risk female adolescents.

    abstract::This study's purpose was to examine the extent to which optimism, knowledge, attitudes, and beliefs predict use of HIV testing services in a group of at-risk female adolescents. We prospectively interviewed 124 consecutive girls engaging in risky behaviors before regularly scheduled pediatric clinic appointments at a ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199511000-00006

    authors: Goodman E,Chesney MA,Tipton AC

    更新日期:1995-11-01 00:00:00

  • Decreased bone mineral density in medicated psychiatric patients.

    abstract::Osteoporosis is a common problem in postmenopausal women. It has been linked to estrogen deficiency, other neuroendocrine processes such as hypercortisolemia and male hypogonadism, nutritional deficiencies, and other mechanisms. Some of these changes have been also reported in male and female patients with mental diso...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199509000-00011

    authors: Halbreich U,Rojansky N,Palter S,Hreshchyshyn M,Kreeger J,Bakhai Y,Rosan R

    更新日期:1995-09-01 00:00:00

  • Psychobiologic reactivity to stress and childhood respiratory illnesses: results of two prospective studies.

    abstract::Psychological stress is thought to undermine host resistance to infection through neuroendocrine-mediated changes in immune competence. Associations between stress and infection have been modest in magnitude, however, suggesting individual variability in stress response. We therefore studied environmental stressors, p...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199509000-00001

    authors: Boyce WT,Chesney M,Alkon A,Tschann JM,Adams S,Chesterman B,Cohen F,Kaiser P,Folkman S,Wara D

    更新日期:1995-09-01 00:00:00

  • Relationships between thyroid hormones and symptoms in combat-related posttraumatic stress disorder.

    abstract::This study was designed to investigate relationships between serum thyroid hormone levels and the severity of posttraumatic stress disorder (PTSD) symptoms in a group of 65 male Vietnam combat veterans who participated as members of cohorts in an elective inpatient treatment program. Thyroid hormone measures included ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199507000-00012

    authors: Wang S,Mason J,Southwick S,Johnson D,Lubin H,Charney D

    更新日期:1995-07-01 00:00:00

  • Physical symptoms of chronic fatigue syndrome are exacerbated by the stress of Hurricane Andrew.

    abstract::This study examined the effects of Hurricane Andrew on physical symptoms and functional impairments in a sample of chronic fatigue syndrome (CFS) patients residing in South Florida. In the months after Hurricane Andrew (September 15-December 31, 1992), 49 CFS patients were assessed for psychosocial and physical functi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199507000-00002

    authors: Lutgendorf SK,Antoni MH,Ironson G,Fletcher MA,Penedo F,Baum A,Schneiderman N,Klimas N

    更新日期:1995-07-01 00:00:00

  • Longitudinal follow-up of amenorrhea in eating disorders.

    abstract::The authors recruited 229 treatment-seeking anorexic and bulimic women for a prospective, longitudinal study. Telephone interviews were arranged every 3 months for at least 1 year for 225 patients. At intake, 132 subjects were menstruating, 34 subjects were taking oral contraceptives, 5 subjects had an organic cause f...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199503000-00004

    authors: Copeland PM,Sacks NR,Herzog DB

    更新日期:1995-03-01 00:00:00

  • Do low cholesterol levels slow mental processing?

    abstract::The plasma cholesterol levels of 279 students were measured and related to decision and movement times in choice reaction time tasks with one, two, four, and eight lamps. In female subjects, low plasma cholesterol levels were associated with slower movement times and, when responding to one or two lamps, slower decisi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199501000-00008

    authors: Benton D

    更新日期:1995-01-01 00:00:00

  • Modeling and reinforcement of the sick role during childhood predicts adult illness behavior.

    abstract::Previous studies suggest that the ways in which parents respond to children's health complaints (reinforcement) and the ways in which they cope with their own illnesses (modeling) influence the frequency of symptoms, disability days, and health care visits made by these children when they grow up. However, previous st...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199411000-00010

    authors: Whitehead WE,Crowell MD,Heller BR,Robinson JC,Schuster MM,Horn S

    更新日期:1994-11-01 00:00:00

  • Selective influence of menstrual cycle on perception of stimuli with reproductive significance.

    abstract::Sixteen healthy women (20-32 years) not taking oral contraceptives were tested at three phases of their menstrual cycles (menses, preovulatory phase, and midluteal phase). Another 16 women taking oral contraceptives served as age-matched controls, and were tested during menses and during phases corresponding to the pr...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199409000-00005

    authors: Krug R,Pietrowsky R,Fehm HL,Born J

    更新日期:1994-09-01 00:00:00

  • The relationship between cardiovascular reactivity in the laboratory and heart rate response in real life: active coping and beta blockade.

    abstract::Earlier studies suggest that cardiovascular responses in the laboratory and in the field are likely to be related when the laboratory tasks involve active coping, when the field measure is taken continuously, and when there is allowance for the effects of autocorrelation and physical activity on the ambulant cardiovas...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199407000-00013

    authors: Johnston DW,Schmidt TF,Albus C,Vagt S,McSorley K,Klingmann I,Bethge H

    更新日期:1994-07-01 00:00:00

  • Effects of chronic stress on beta-adrenergic receptors in the homeless.

    abstract::This study examined the role of chronic life stress (homelessness), coping style, and hypertension on beta-adrenergic receptors in a sample of homeless men. Sixteen healthy normotensive subjects and nine untreated hypertensive subjects were studied. Life stress was measured with the Brown and Harris categorization; co...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199407000-00003

    authors: Dimsdale JE,Mills P,Patterson T,Ziegler M,Dillon E

    更新日期:1994-07-01 00:00:00

  • Alexithymia may influence the diagnosis of coronary heart disease.

    abstract::A number of psychosomatic studies have suggested that alexithymia, impairment in identifying and expressing inner feelings, might somehow affect the course of various illnesses. However, none of these studies have distinguished between an impact of alexithymia on actual pathophysiological change versus an impact only ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199405000-00010

    authors: Kauhanen J,Kaplan GA,Cohen RD,Salonen R,Salonen JT

    更新日期:1994-05-01 00:00:00

  • Intervention for minor depression in primary care patients.

    abstract::This study examines the effectiveness of an intervention for minor depression in primary care patients. One hundred fifty public care medical patients were randomly assigned to either an 8-week cognitive-behavioral course intended to help them use pleasant activities, constructive thinking, and interpersonal relations...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199403000-00009

    authors: Miranda J,Muñoz R

    更新日期:1994-03-01 00:00:00

  • Cardiovascular and neuroendocrine responses to extended laboratory challenge.

    abstract::The purpose of this study was to examine the effects of a 2-hour laboratory challenge on heart rate, blood pressure, catecholamines, and cortisol; and investigate the contribution of the physical act of speaking on both neuroendocrine and cardiovascular measures. Using a within-subjects design, 14 subjects were tested...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199311000-00005

    authors: McCann BS,Carter J,Vaughan M,Raskind M,Wilkinson CW,Veith RC

    更新日期:1993-11-01 00:00:00

  • Negative behavior during marital conflict is associated with immunological down-regulation.

    abstract::Although increased morbidity and mortality have been reliably associated with social isolation and less satisfying personal relationships, relatively little is known about the underlying biopsychosocial mechanisms. We assessed problem-solving behaviors and changes in immune function in 90 newlywed couples who were adm...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199309000-00001

    authors: Kiecolt-Glaser JK,Malarkey WB,Chee M,Newton T,Cacioppo JT,Mao HY,Glaser R

    更新日期:1993-09-01 00:00:00

  • Dependence between apolipoprotein E phenotypes and temperament in children, adolescents, and young adults.

    abstract::The association of apolipoprotein E (apoE) polymorphism with temperament and Type A behavior was studied in 1577 randomly selected healthy children, adolescents, and young adults during a follow-up period of 9 years. Temperament was correlated with apoE phenotypes. Motor activity, even hyperactivity, in childhood and ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199303000-00004

    authors: Keltikangas-Järvinen L,Räikkönen K,Lehtimäki T

    更新日期:1993-03-01 00:00:00

  • Hypertension affects neurobehavioral functioning.

    abstract::This study compared the neurobehavioral performance of hypertensive and normotensive men and women using neuropsychological, information-processing, and psychometric assessments. One hundred subjects, including 68 hypertensive and 32 normotensive individuals, completed a test battery that yielded scores on measures of...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199301000-00008

    authors: Blumenthal JA,Madden DJ,Pierce TW,Siegel WC,Appelbaum M

    更新日期:1993-01-01 00:00:00

  • Eating habits and eating disorders during pregnancy.

    abstract::A general population sample of 100 primigravid women was studied prospectively to describe the changes in eating that occur in pregnancy with particular reference to cravings and aversions and the behavior and attitudes characteristic of clinical eating disorders. Assessment was by standardized interview. Dietary crav...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199211000-00006

    authors: Fairburn CG,Stein A,Jones R

    更新日期:1992-11-01 00:00:00

  • Effects of psychological treatment on cancer patients: a critical review.

    abstract::Twenty-two studies on the effects of psychological treatment on cancer patients are reviewed. Only studies that compared one or more experimental conditions with at least one control group have been considered. The studies were evaluated with respect to a) research methods, b) psychological interventions, and c) resul...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199207000-00011

    authors: Trijsburg RW,van Knippenberg FC,Rijpma SE

    更新日期:1992-07-01 00:00:00

  • Effects of coffee on cardiovascular responses to stress: a 14-week controlled trial.

    abstract::We studied the cardiovascular responses to orthostatic and mental stress of 43 healthy subjects who daily received six cups of boiled or filtered coffee and of 21 healthy subjects who abstained from caffeine-containing beverages. All 64 subjects first received six cups of filtered coffee/day for 2 weeks. Then blood pr...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199205000-00010

    authors: van Dusseldorp M,Smits P,Lenders JW,Temme L,Thien T,Katan MB

    更新日期:1992-05-01 00:00:00

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